The Mouse Anti-hnRNP U [3G6] Antibody from MyBioSource.com is a Mouse Monoclonal antibody to hnRNP U, HNRNPU, and SAFA. This antibody recognizes Human, Mouse, and Non-Human Primate antigen. The Mouse Anti-hnRNP U [3G6] Antibody has been validated for the following applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunoprecipitation, and Western Blot.
Description
The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm The hnRNP proteins have distinct nucleic acid binding properties hnRNP U is thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes During apoptosis this protein is cleaved in a caspase-dependent way